Republic of Cyprus
Republic of Cyprus - Department of Labour Inspection


Article 45 of the CLP Regulation

According to Article 45 of the CLP Regulation, companies placing hazardous mixtures on the market are obliged to provide information about certain hazardous mixtures to the relevant national bodies. The national bodies make this information available to Poison Centres so that they can give advice to the citizens or medical personnel in the event of an emergency. Information is submitted for products classified as hazardous on the basis of their health or physical effects (toxic, harmful, irritant, corrosive, flammable, oxidative) .
The National Appointed Body IN CYPRUS is the Department of Labour Inspection (DLI).

ECHA PCN Portal can be found in ECHA’s webpage.

As from 1.1.2021 all future notifications / updated notifications must be submitted via ECHA Submission Portal ONLY. 

For all ‘new’ products which were NOT notified under the previous national notification procedure, the companies must submit the required information VIA ECHA SUBMISSION PORTAL before the mixture is placed on the market.

PCN portal will be used for all Consumer, Professional and Industrial mixtures according to the above dates and all obligations can be found in Annex VIII of CLP Regulation.

Submissions should be made according to the relevant date of applicability:

  • 1 January 2021 for consumer or professional use;
  • 1 January 2024 for industrial use

Frequently Asked Questions and Important Notes :

  1. As of 1.1.2025, all past notifications submitted nationally have to be RE-SUBMITTED via ECHA PCN Portal. The national notification procedure is no longer valid. 
  2. Companies that have submitted their notifications using the national procedure until 31.12.2020 can take advantage of the transitional period and their notifications will remain valid until 31.12.2024 unless there is an update of the notification. In cases of updates, the notifications have to be re-submitted through ECHA Submission Portal.
  3. Notifications submitted before 1.1.2021 via the ECHA Submission Portal are not considered as valid if CYPRUS market was not included in the notifications. For these cases there is a need to update past notifications and include CYPRUS in order for the Appointed Body to have access to them.
  4. Suppliers / importers are urged to submit the notifications before placing their products on the Cyprus market
  5. No fee is required for the submissions, nor for the placing of the products on the national market.
  6. Once submitted via ECHA Submission Portal and passed all validations rules, the notifications are considered valid by the Appointed Body.
  7. No further approval or confirmation is provided by the Appointed Body regarding the submissions.
  8. The Appointed Body has the right to request further related information by the submitters if needed.
  9. After notification, the companies have to place the UFI numbers on the labels of the products placed on the Cyprus market.


  1. The CYPRUS POISON CENTER Number (emergency telephone number) to be included in point 1.4 of the SDS of the products placed on the Cyprus market, is 1401. The use of 1401 is free.
  2. The contact point for the Appointed Body in Cyprus is Dr Maria Paleomilitou (tel. +35722405611,

  • In case of emergency, the data are forwarded to the Cyprus Poison Center.
  • All information is kept strictly confidential.


    Webinar: Poison centres: closing in on the first compliance date Questions and answers


    Annex VIII to the CLP Regulation, adopted in March 2017, defines the harmonised requirements for poison centre notifications (PCN) applicable as of 1 January 2021.

    Under Annex VIII, importers and downstream users placing hazardous mixtures on the EU market are obliged to provide specific information on their mixtures to the specified Appointed Bodies using a Harmonised Format for notifications (PCN Format). The information contained in the notifications will be used by Poison Centres for emergency health response purposes in case of incidents involving these mixtures.

    ECHA has developed IT tools to support preparing, submitting and receiving information on hazardous mixtures.

    More information

    Κατεβάστε το αρχείο Acrobat EU importers and UK suppliers.pdf

    Κατεβάστε το αρχείο Acrobat legal-submitters-foreign-users_en.pdf

    Κατεβάστε το αρχείο Acrobat ATT26I2M.pdf

    Κατεβάστε το αρχείο Acrobat what_is_a_ufi_en.pdf

    Κατεβάστε το αρχείο Acrobat ufi_what_it_means_en.pdf

    Κατεβάστε το αρχείο Acrobat guidance_on_annex_viii_to_clp_en.pdf

    Κατεβάστε το αρχείο Acrobat 3-Managing_your_UFI.pdf

    Κατεβάστε το αρχείο Acrobat 2-Creating_and_using_your_UFI.pdf


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